The Pathology Department in Theodor Bilharz Research Institute is one of the basic pillars of the clinical and research activities.It has a highly qualified and well trained staff, having long years of experience. The department is well equipped by the most recent tools used in the field of pathology world-wide. We used to hold periodic training programs, and we always welcome and encourage conjoint work with our colleagues in universities and research centers.



PUBLICATIONS

Publications (2000-2013):
1.      EL-Ahwany E., Hanallah S., EL-Ghorab M., Badir B., Badawy A., Sharmy R., Hassanein H. (2000). Immunologicalization of macrophage adhesion molecule1 and macrophage inflammatory protein-1 in schistosomal soluble egg antigen induced granulomatous hyporesponsiveness. Int. J. Parasitol. 3:837-842.
2.      Kamel G., Metwally A., Guirguis F., Nessim N., Nosseir M. (2000). Effect of combination of the new antischistosomal drug Ro 15-5458 and praziquantel on different strains of Schistosoma mansoni infected mice. Arzneimittel-Forschung/Drug Research. 50: 391-394.
3.      Abdel Hadi A.M. and Talaat M. (2000). Histological assessment of tissue repair after treatment of human schistosomiasis. Acta Tropica, 77: 91-96.
4.      Maklad Y.A. and Nosseir M.M. (2000). Androgenic and anabolic activities of some newly synthesized epiandrosterone and progesterone derivatives. Scientia Pharmazeutica (Sci. Pharm.) 68, 141-157.
5.      Saber M.A., Reda M.A., El Malatawy M.A., Sadek A., Abou Shousha T. (2000). Immunohistochemical study of Ki-67 antigen for early detection of esophageal metaplasia in gastro-esophageal reflux disease (GERD). Sci. Med. J. ESCME. 12: 3.
6.      Helmy A.H., Abou Shousha T., Magdi M., Sabri T. (2000). Appendicitis; Appendectomy and the value of endemic parasitic infestation. Egypt. J. Surg. 19: 78-184.
7.      Abu Zekri N., Kamel L., Akl M., Sadek A., Morsy A., Bibawi H., Aboushousha T., Mekkawy Y. (2000). Diagnostic accuracy of hyaluronan, telopeptide, collagen type IV-7S and type III procollagen amino-terminal peptide serum assays as non-invasive biomarkers of liver fibrosis in chronic viral hepatitis C evaluated by ROC curve analysis. Med. J. Cairo Univ.  68: 137-146.
8.      Nosseir M., Metwally A., Kamel G., Guirgis F., Nessim N. (2000): Evaluation of the effect of RO15-5458 and combined anti-schistosomal drugs on different strains of Schistosoma mansoni infected albino mice: Histopathological and parasitological study. Egypt. Schisto. Infect. Endem. Dis. 22: 115-136.
9.      Bekheet I.W., Issawy F.M., Nosseir M.M., El-Sherief N.H., Sadek A. (2000). Immunohistochemical  and serological studies of basic fibroblast growth factor in chronic liver diseases and hepatocellular carcinoma. Egypt. J. Pathol. 20: 309-318.
10.  El-Defrawi I., Diab M., Moussa M., El-Ray A., El-Sherbini E. (2000): Rapid non-invasive diagnosis of Helicobacter pylori in dyspeptic patients. Egypt. J. Med. Microbiol. 9: 219-227.
11.  El Baz H.G.,Wishahi M.M., Hammam O.A. (2000): Expression  of  P53 and C erb-B2 oncoprotein   in chronic schistosomal  urinary bladder lesions. Kasr El Aini . Med. J. 6: 503-518.
12.  Helmy A.H.I., Hammam O.A. (2000): Inflammatory response in the fixation of proline mesh N buteyl 2cyanoacrylate (Histoacryle) in abdominal wall: Experimental study.  Egypt. J.  Surg. 19: 289-295.
13.  Hammam O., Riad E., Akl M., Hindawi A., Abdel Hadi A., El Sherif E. (2000): Clinical significance of DNA content analysis (ploidy) and morphometric measurement in schistomal transitional cell carcinoma to chronic schistosomal cystitis, Transitional cell papilloma G0 and normal urothelium with its application in urine samples.  Kasr El Aini  Med. J. 6: 349-364.
14.  Akl M.M., El-Hindawi A.F., Hammam O.A., Abou-Shousha T., El-Baz A.G.,  Abdel Hadi A.M., Badawy A.A. (2001). Predictive value of Ki67 expression in schistosomal associated bladder lesions versus non schistosomal ones in correlation to urothelial ploidy and morphometric parameters. J. Eu. Soc. Pathol.  3: 393.
15.  Hassan S.I., Nessim N.G., Mahmoud S.S., Nosseir M.M. (2001). Effect of broad spectrum anti-parasitic drug “Ivermectin” in acute and chronic experimental giardiasis using different dose regimens. J. Egypt. Soc. Parasitol. 2: 419-430
16.  William S., Sabra A., Ramzy F., Moussa M., Demerdash Z., Bennett J., Day T. and Botros S. (2001). Stability and reproductive fitness of Schistosoma mansoni isolates with decreased sensitivity to praziquantel. Int. J. Parasitol. 31: 1093-1100.
17.  EL-Bassiouni N., EL-Sayed H., Lotfy M., Badawy A.A., Roshdy M., Asaad S., Iskander J.  (2001): Modulation of ABH and Lewis antigen expression in cancer bladder associated with schistosomiasis.  Kasr EL-Aini Med. J. 7: 201-215.
18.  Rizk H.A., Abou Shousha T. (2001). The identification of a novel Helicobacter species in cholecystitis specimens; A preliminary study. Kasr El Aini J. Surg.  2: 19-23.
19.  Rizk H., Reda M.F., Ezzat H., Abou Shousha T., Nosseir M. (2001). The possible role of Helicobacter like species in the aetiology of chronic cholecystitis in patients with positive gastric Helicobacter infection. Kasr El Aini J. Surg. 2: 113-116.
20.  Saber M., Ahmed H., Abu-Aitta A., El-Defrawi I., Saad El-Din S., Moussa M., Shoman M., Mikhail N., Helmy A. (2001). Identification of Helicobacter sp. in bile and resected gall bladder tissue from Egyptians with chronic calcular cholecystitis. Az. J. Microbiol.  52: 107-116.
21.  Abbas M., Youssef Y., Hazem A., Nafeh A., Moussa M., Naseem I. (2001).  The Effect of intra-abdominal hypertension during pneumoperitonium on enzymatic liver functions and architect. The role of corticosteroids, prostaglandin's and adenosine triphosphate in prophylaxis: A comparative experimental controlled study.  Egypt. J. Surg.  20: 412-417.
22.  Diab M., El-Serif N., Moussa M., Ahmed H., El-Assaly N., El-Ghannam M.,  El-Ashry N., Akl M. (2001). Autoimmunity in chronic liver disease: Clinical, serological and immunohistochemical correlations. Egypt. J. Med. Microbiol. 10: 227-238.
23.  Demerdash Z., Moussa M., El-Baz H., Salah F., El-Baz A., Akl M. (2001).  Tissue localization of Schistosoma haematobium antigens and expression of p53 and cytokeratin18 in different urinary bladder lesions. Kasr El-Aini Med. J. 7: 355-375.
24.  Essawy M.M., El-Bee A., Ezzat H., Abbas M., El-Batanouny M.,   Nosseir M.M., Omran Z.S., Khaled I.A. (2001).  Effect of splenectomy on liver fibrogenicity in portal hypertension patients. Egypt. J.  Surg. 20: 722-728.
25.  El Ray A., Fam N., Aboul Fadl L., Hammam O., Ahmad H Akl M., El Sherbini., Saber H. (2001). Monitoring of successful eradication of Helicobacter pylori by endoscopic, serologic, molecular and histopathological methods in Egyptian dyspeptic patient. Kasr El Aini. Med. J.  7: 195-221.
26.  Saber M.A., Sherief S.A., Nosseir M.M. (2001).  Experimental trial of immunoisolated, immunomodulated hepatocyte transplantation in acute fulminant hepatitis. The Sixth Annual International Congress of Egyptian Society of Tropical Medicine, Infectious And Parasitic Diseases (ESTIP). June 27th – 29th 2001, Palestine Hotel, Alexandria, Egypt. Abstract book, page 60.
27.  El Baz H.G., Hammam O.A., Hanallah S.B., El Baz A.G., Giguis B.M., Guafar T. (2001). Vascular endothelial growth factor: An important angiogenic mediator in chronic bladder lesions.  Kasr El Aini. Med. J. 7: 29-47.
28.  Mahmoud S., Demerdash Z., Mohamed S., Badawy A.A., Mohamed S., Shaker Z., Ibrahim A. (2002). Study of kinetics of circulating schistosome antigens in tissues and sera of infected mice using anti-Schistosoma mansoni soluble egg antigen monoclonal antibody. Egypt. J.  Schisto Infec. Endem. Dis. 24:1-17.
29.  Salah F., Hassanein H., Hassan S., Sayed S., Badawy A. (2002). The dynamics of serum and hepatic schistosomal antigens in two different strains of mice. Egypt. J.  Schisto Infec. Endem. Dis.  24: 19-36.
30.  Mahmoud M.R., Zohairy M.K., Nosseir M.M.F. (2002). Effect of combined chemotherapy and anti-inflammatory drugs on murine schistosomiasis.  Arzneimittel-Forschung/Drug Research 52: 294-301.
31.  Badawy A.A., Hammam O.A. (2002): E-cadherin and epithelial membrane antigen expression in schistosomal urinary bladder lesions. J. Egypt. Soc. Path. 22:283-290.
32.  El-Wakil H.S., Aboushousha T.S., El-Haddad O.,  Gamil N.B., Mansour T., El-Said H. (2002). Effect of Schistosoma mansoni egg deposition on multiple low doses streptozotocin induced insulin dependent diabetes. J. Egypt. Soc. Parasitol. 32: 987-1002.
33.  Abou Shousha T., Moussa M., El-Khayat H., Yehia H., Seif S. (2002). Expression of Ki-67 and human Papilloma virus in premalignant and malignant eosophageal lesions. J. Egypt Soc. Path.  22: 291-299.
34.  Mahmoud F., Moussa M., Mahmoud S. (2002). Detection of Schistosoma haematobium antigens in serum and urinary tract tissue of infected hamsters using specific monoclonal antibody. Kasr El-Aini Med. J. 8: 51-66.
35.  Hanallah S., Mahmoud S., Moussa M., Botros S. (2002). Altered immunoglobulin isotype profile and anti-immature worm surface immunoglibulins G & M in mice harboring a praziquantel resistant Schistosoma mansoni isolate.  Kasr El-Aini Med. J. 8: 265-281.
36.  Nessim I., Abu Zikri N., Moussa M., Hafez T., Hazem A., Reda M., Abdel-Hadi A., Edward N., El-Ghafir W. (2002). Implication of tumor necrosis factor alpha (TNF-α), interleukin beta (IL-1ß) and intercellular adhesion molecule-1 (ICAM-1) in warm hepatic ischaemia reperfusion injury: Effect of intraportal infusion of prostaglandin E1. Egypt. J. Lab. Med. 14: 243-274.
37.  Moussa M., Hammam O., Hassan E., Turky E., Seif S., Youssef M. (2002). Study of immune response and apoptosis in Helicobacter pylori-associated gastric lesions. J. Egypt. Soc. Path. 22: 301-309.
38.  Bekheet I., Zahran N., Nosseir M., Ibrahim A., Wilson M., Mostafa I.,   Essawy F. (2002). Clinical significance of angiogenic and fibrinolytic factors in chronic liver disease and hepatocellular carcinoma. Egypt. J. Lab. Med. 14, 1.
39.  Akl M.M., Hammam O.A., El Baz H.G., Demerdash Z.A., Sadek  A., Mostafa I. (2002). Expression of intercellular adhesion molecules ICAM-1 and cytokeratin as potential markers of disease activity in the Egyptian pattern of chronic hepatitis C.  Med. J. Cairo Univ.  70 (1): 211-222.
40.  Badawi H., Ahmed H., Diab M.S., Aboul Fadl L., Helmi A., El-Khafif N., Omran Z., Tosson W., Akl M., Saber M.A. (2002). Role of Cytomegalovirus (CMV) and Epstein-Barr Virus (EBV) in urinary bladder cancer: Microbiological, molecular, pathological and electron microscopic characterization. Egypt. J.  Med.  Microbiol. 11 (4): 861-875.
41.  Abdel Hadi A.A., Desouky A.M., El Damrawi M., Hammam O.A., Sadek A.,  Abdel Hadi A. (2002). Th1/Th2 serum cytokines imbalance and their relevance to severity of disease in HCV-related liver cirrhosis. Egypt. J. Internal Med. 13:  227-238.
42.  Hammam O.A., Tosson W., Kamel A.I., Moustafa A., Mehena A.A., Hady A.A. (2002). Prognostic significance of tumor angiogenesis in superficial bladder tumors. Egypt. J. Pathol.  23: 231-238.
43.  Botros S., William S., Hammam O., Zidek Z., Holy A. (2003). Activity of 9-(S)-{3-hydroxy-2-(phosphonomethoxy) propyl} adenine against schistosomiasis mansoni in mice. Antimicrobial Agents and Chemotherapy. 3853-3858.
44.  Abou Shousha T.S., Yehia H.A., Badawy A.A. (2003). Focal hepatic lesions; cytopathological and clinico-ultrasonographic survey in endemic locality. Kasr El- Aini Med. J. 9: 57-68.
45.  El-Assaly N., El-Ray A., Abou Shousha T. (2003). Clinical, sonographic, biochemical and histopathological assessment of hepatic steatosis in Egyptian patients with HCV and HCV associated HCC Kasr El-Aini Med. J. 9: 191-207.
46.  Badawi H., Ahmed H., Ismail A., El-Khafif N., Helmy A., Badawy A.A., Mansy S., Saber M.A. (2003). Role of human papillomavirus 16 in urinary bladder cancer: New approach for detection of antiviral IgG in correlation to detection of the virus by electron microscopy or viral DNA by PCR.  Egypt. J. Med. Microbiol. (EJMM). 12: 741-756.
47.  Zakaria S., Akl M., Nosseir M., Amer A., Anwar H., and Abu-Madian M. (2003). Clinico-pathologic profile of non-alcoholic hepatic steatosis in Egypt. Proceedings of the XIV Annual Congress of ESLM. pp. 1-18.
48.  Abbas M., Omran Z., Nosseir M. (2003). Histopathological assessment of the effect of non-absorbable prosthetic mesh on the spermatic cord contents: An experimental study. Egypt. J. Surg.  22: 223-231.
49.  Zoheiry M.K., Nosseir M.M., El-Ahwany I.G. (2003). Down-regulation of intercellular adhesion molecule-1 (ICAM-1) and lymphocyte funtion-associated antigen-1 (LFA-1) on chronic hepatic murine schistosomiasis mansoni. Kasr El-Aini Med. 9:  99-116.
50.  Saber M.A., Abou Shousha T.S., Ahmed M.H., Romeih M.H., Sadek A, Abdel Hady A.M. (2003).  Reliability of histopathological and molecular techniques for diagnosis of hepatitis B and C viruses in chronic liver diseases. Kasr El Aini Med. J.  9: 123-140.
51.  El-Lakkany N.M., Seif El-Din S.H., Badawy A.A., Ebeid F.A. (2004). Effect of artemether alone and in combination with grapefruit juice on hepatic drug-metabolising enzymes and biochemical aspects in experimental Schistosoma mansoniInt. J. Parasitol. 34:1405-1412.
52.  Badawy A.A., El-Hindawy A.A., Khattab H.M., Abo-Shousha T.S, El-Shahat N.S., Omran Z.S. (2004). Significance of P21 and C-myc expression in bladder urothelial    lesions.  J. Egypt. Soc. Path. 23: 277-284.
53.  Moussa M., Nosseir M., Omran Z., Guirguis N., Yehia H., El-Khayat H., Siam M., Yousef M. (2004). Occurrence of gastro duodenal giardiasis and/or Helicobacter pylori infection after gastric acid suppression. Egypt. J. Pathol. 24:  61-68.
54.  Badawy A.A., Nosseir M.M., Moussa M.M. (2004). Immunoreactivity of p53 and Ki-67 in some chronic urinary bladder lesions. Kasr El-Aini Med. J. 10: 85-94.
55.  Seif El-Din S.H., El-Lakkany N.M., Badawy A.A., Ebeid F.A. (2004). Inhibitory effect of grapefruit juice co-administration with praziquantel on some hepatic microsomal enzymes in murine Schistosoma mansoni. Kasr El Aini Med. J.  10:51-62.
56.  Akl M., Zakaraia S., El-Hindawi A., Hammam O., Yehia H., El-Raziky M., Ibrahim R., Fakhry S., El-Behairy N. (2004). Impact of apoptosis on the severity of chronic hepatitis C in a sample of Egyptian patients. J. Egypt Soc. Path. 24:317-331.
57.  Abou El Eila G.M., Barsoum H.B., Omran Z., Kamar S.A. (2004). Clinico-pathological study of 9 cases of gastrointestinal stromal tumors. New Egypt. Med.  31: 387-391.
58.  Akl M.M., Hammam O.A., Hassanein M., El Ghannam M., Abou Shousha T.S., El Ray A., Kishta S.A. (2004). Role of apoptosis in Egyptian endemic chronic liver diseases: Immunohistochemical study.  Kasr El Aini Med. J. 10: 219-232.
59.  El-Shazly S.H., Hammam O.A., Abdel Salam M., El-Hady A.M. (2004). Immunohistochemical detection of Fas expression and Bcl2 in liver tissues of patients with chronic liver diseases. Sci. J. Az. Med. Fac. (Girls) 25: 831-848.
60.  Hassan S.I., Ali I., Nessim N.G., Amer N.M., Nosseir M., El-Khafif M.A., Ashour A., El-Mohandes M. (2004). Egg excretory pattern with respect to hepatic collagen content in chronic Schistosoma mansoni-infected mice given praziquantel and an anti-fibrotic. Kasr El-Aini Med. J. 10: 33-40.
61.  Romeih M.H, Hanem M.A., Abou Shousha T.S., Saber M.A. (2005). Vaccination against Schistosoma mansoni infection by DNA encoding SM 21.7 antigenNature and Science. 3: 28-35.
62.  Akl M., Zakaria S., El-Hindawi A., Hammam O., Yehia H., El Raziky M., Ibrahim R., Fakhry S., El Behairy N. (2005). Impact of apoptosis on the severity of chronic hepatitis C. Virchows Archiv.  447: 297.
63.  Badawy A., Hammam O. (2005). Hepatic expression of endothelial nitric oxide synthase (ENOS) and vascular endothelial growth factor (VEGF) in chronic hepatitis C and schistosomal liver disease. Virchows Archiv.  447: 298.
64.  Badawy A., EL-Hindawy A., Khattab H., Abo-Shousha T., El-Shahat N., Omran Z. (2005). Significance of P21 and C-myc expression in bladder urothelial lesions. Virchows Archiv. 447: 347-348.
65.  Badawy A., Nosseir M., Moussa M. (2005). Prevalence of p53 and Ki-67 immunoreactivity in chronic urinary bladder lesions. Virchows Archiv. 447: 355.
66.  Badawy A., Hammam O. (2005). E-cadherin and epithelial membrane antigen expression in schistosomal urinary bladder lesions. Virchows Archiv. 447: 355.
67.  Akl M., Zakaria S., Hammam O., El Raziky M., Yehia H.,  Fakhry S., Seyma M., Ibrahim R., El-Hindawi A., El Behairy N. (2005). Hepatocyte apoptosis in chronic hepatitis C: A prominent feature of disease severity in Egyptian patients. Virchows Archiv. 447: 300-301.
68.  Hazem A.I., Abdel-Hady A.A., El-Shanawany F., Hammam O., Abdel-Hady A.M. (2005). The pharmacological approach to reverse portal hypertention and hepatic schistosomal fibrosis in Egypt: Control experimental study. J. Egypt. Soc. Parasitol. 35: 731-750.
69.  Zakaria S., Akl M., Nosseir M., El Raziky M., Amer A., Anwar H., Abu-Madian A. (2005). Hepatic steatosis in Egypt. A clinical and pathological profile. Virchows Archiv. 447: 301-302.
70.  Zakaria S., Akl M., Nosseir M., El-Serafy M., Abul-Ezz M. (2005). The use of argon plasma coagulation (APC) in portal hypertensive gastropathy (PHG). Accepted for publication in World Journal of Gastroenterology (WJG) on (28-2- 2005). Printed in China.
71.  Mahmoud M., Ebeid F., Nosseir M. (2005):  Enhanced role of grapefruit juice on the anti-schistosomal activity of artemether on the liver of Schistosoma haematobium infected hamsters. Scientia Pharmazeutica (Sci. Pharm.) Under press (2005).
72.  Saleh S., Mahmoud M., El-Abhar H., Omran Z. (2005). Anti-schistosomal effect of thymoquinone in murine schistosomiasis mansoni: Influence on nitric oxide, ICAM-1 and collagen. Kasr El-Aini Med. J. 11: 117-127.
73.  El Mohandes M.Y., Omran Z., El Khayat H.R. (2005). High grade of hepatitis C virus activity is associated with up-regulation of circulating interleukin-10 level. Kasr El-Aini Med. J. 11: 155-161.
74.  Akl M., Nosseir M. Badawy A.A., El-Baz A., Roshdy M.,  El-Leithy T. (2005). Histopathologic assessment of angiogenic response in different urinary bladder lesions. Proceedings of the XVI Annual Congress of ESLM, March 2005.
75.  El-Khafif N., Yehia H., Hammam O., Mahmoud S., Helmy A., Boehm S., Voss B., Mansy S., Akl M., El Fandy G. (2005). Ultrastructural hepatic changes after bone marrow transplantation in murine schistosomiasis. Kasr El Aini Med. J. (Under press) 2005.
76.  Zakaria S., Akl M., Hammam O., El Raziky M., Fakhry S., Seyam M., Yehia H., Ibrahim R., El Hindawi A., El Behairy N. (2005). Hepatocyte apoptosis in chronic hepatitis C: A prominent feature of disease severity in Egyptian patients. J. Hepatol. Gasteroenterol. Infect. Dis. 10: 31-44.
77.  Akl M.M., Hammam O.A., Helmy A.H.I., Mahgoub M.A., Ammar A., Ashmawi H.A.A. (2005). The sub-deltoid versus intra-peritoneal implantation of canine macro-capsule allogenic amniotic membrane; assessment of rejection and neo-vascularization. Egypt. J. Surg. 24: 73-80.
78.  Hassan S.I., Ali I., Nessim N.G., Amer N.M., Nosseir M., El-Khafif M.A., Ashour A., El-Mohandes M. (2005). Transmission hepatic electron microscopic findings in acute experimental schistosomiasis mansoni after praziquantel and an anti-fibrotic. Kasr El-Aini Med. J., 11: 23-28.
79.  Ebeid F., El-Lakkany N, El-Deen S.S., Sabra A., Nosseir M., Botros S. (2005). Effect of mirazid against different developmental stages of Schistosoma mansoni worms and its safety in normal mice. Egypt. J. Schisto. Infect. Endem. Dis.  27: 15-24.
80.  Hammam O., Roshdy M., Abou Shousha T., Aziz A. (2006).  Possible role of cyclooxygenase-2 in Schistosoma-and non-Schistosoma associated bladder cancer. Kasr El Aini Med. J. 12: 99-108.
81.  Omar M., Fam N., Saad El-Din S., Romeih M., Mohamed H., Hassan M., Mostafa I., Badaway A., Akl M., Saber M. (2006). Torque teno virus (TTV) infection in Egyptian patients with chronic liver disease and hepatocellular carcinoma. Nature and Science. 4: 38-45.
82.  El-Ahwany E., Nosseir M.M., Aly I.R. (2006). Immunomodulation of pulmonary and hepatic granulomatous response in mice immunized with purified lung-stage schistosomulae antigen. J. Egypt. Soc. Parasitol. 1: 335-350.
83.  El-Bassiouny A., Nosseir M., Zoheiry M., El-Ahwany E., Ghali A., El-Bassiouni N. (2006). Immunohistochemical expression of CD95 (Fas), C-myc, and epidermal growth factor receptor in hepatitis C virus infection, cirrhotic liver disease and hepatocellular carcinoma. Acta Pathol, Microbiol Immunol Scandinavica (APMIS) 114:  420-427.
84.  El Bassiouny A., El Ahwany E., Abou Shousha T., Moussa M., El Bassiouni N., Maher K., Galli A., Youssef M., Suher Z. (2006).  Hepatic mRNA expression of histone (H3): An early predictor of tumorgenic changes in chronic hepatitis C. J Gastroenterol. Hepatol. 21, (Suppl. 2), Abstract ≠ 297, p A164. * Accepted at Shanghai–Hong Kong International Liver Congress "Drug Discovery for the Treatment of Liver Diseases” ,  Shanghai, China.
85.  Botros S., Mahmoud M., Hammam O., Salah F., Zidek Z., Masek K. (2006). Effect of adamantylamide dipeptide as adjuvant therapy to praziquantel in mice infected with different S. mansoni isolates. Acta. Pathol. Microbiol. Immunol. Scandinavica (APMIS). 114: 480-491.
86.  Helmy A., Hammam O., El Leithy T., Wishahi M. (2007). The role of TGF-beta-1 protein and TGF-beta-R-1 receptor in immune escape mechanism in bladder cancer. Medscape-General-Medicine (MedGenMed) 9:34.
87.  El-Lakkany N., Nosseir M. (2007). Pharmacodynamics of  pentoxifylline and/or praziquantel in murine schistosomiasis mansoni. Acta. Pathol. Microbiol. Immunol. Scandinavica (APMIS) 115: 184-194.
88.  El-Bassiouny A., Zoheiry M., Nosseir M., El-Ahwany E., Atta R. El-Bassiouni N. (2007). Expression of cyclooxygenase-2 and trasforming growth factor-β1 in HCV-induced chronic liver disease and hepatocellular carcinoma. MedGenMed; www.medscapegeneralmedicine.com   US 2007; 9 (3):45© 2007 Medscape.
89.  Botros S.S., Mahmoud M.R., Moussa M.M., Nosseir M.M. (2007). Immunohistopathological and biochemical changes in Schistosoma mansoni-infected mice treated with artemether.  J. Infection. 55: 470-477.
90.  Abbas M., Farouk Y.,  Nafeh A., Nasr M., Nosseir M., Zoheiry M. (2007). Regenerative potential of cirrhotic liver following selective extra-hepatic vascular ligation: An experimental study. Kasr El-Aini J. Surg. 8:  75-84.
91.  Kamel M., Maher K., Nosseir M., El-Bassiouni N., El-Bassiouny A., Ghali A.,  (2007). Frequency of HLA-DRB1*alleles in patients with hepatitis C virus infection: Relevance to clinical outcome. Kasr  El Aini Med. J. 13: 75-82.
92.  Saber M.A., Diab T., Nosseir M.M., Mohareb M.N., El-Dabaa E. (2007). DNA vaccination using Schistosoma mansoni fimbrin gene on naive and infected praziquantel-treated mice. New Egypt. J. Med. 37: 24-34.
93.  Nafeh A.I., Nosseir M.M. (2007). Assessment of peritoneal adhesions due to starch granules of surgical glove powder: An experimental study. J. Egypt. Soc. Parasitol. 37: 835-842.
94.  Sadek A, Abd El Hady A M, Hammam O, Elbasha H, Abd El Hady A (2007). Effect of ozone gas with and without anti-oxidants on viral kinetics and liver histopathology, in hepatitis C patients: A phase II clinical study. Accepted for publication in World Journal of Gastroenterology (WJG), on (9- 4- 2007).
95.  Hafez T., Moussa M., Nesim I., Baligh N., Davidson B., Abdul-Hadi A. (2007). The effect of intraportal prostaglandin E1 on adhesion molecule expression, inflammatory modulator function, and histology in canine hepatic ischemia/reperfusion injury. J. Surg. Res. 138: 88-99.
96.  Essawy MM, Nafeh AI, Ezzat HM, Elsebae MM, Marei SA, Salama AF, Badawy AA. (2007). The effect of  portal vein branch plus heterochronous hepatic artery branch ligation on liver regeneration (experimental study). J. Egypt. Soc. Parasitol. 37 (2): 557-570.
97.  El Bassiouny A., Zoheiry M., El-Ahwany E., Salah F., Nosseir M., Omran Z.,  Atta R., El-Bassiouni N. (2008).  Circulating and hepatic Fas expression in HCV-induced chronic liver disease and hepatocellular carcinoma. Medscape J Med. www.medscapegeneralmedicine.com USA; 10 (6):130.  ©2008 Medscape
98.  Fahmy Z.H., Mohammed A.H., Nosseir M.M. (2008). Ultrastructural and histopathological changes in Giardia Lamblia-infected hamsters following administration of two natural compounds and/or metronidazole.  New Egypt. J. Med. 38: 53-61.
99.  Youssef F.Y., Nosseir M.M. (2008). Effect of increased intra-abdominal pressure due to pneumoperitoneum on liver functions and liver histopathology in a rat model with intra-abdominal sepsis. J. Egypt. Soc. Parasitol. 38: 161-170.
100.  Badawy H., Ahmed H., Ismail A., Diab M., El-Din S.S., Nosseir M.M., Omran Z., Saber M. (2008). Human Papilloma virus DNA and p53 protein expression among Egyptian patients with urinary bladder cancer in relation to schistosomiasis and clinico-pathologic outcome. Egyp. J. Med. Microbiol. 17:  593- 603.
101.  Hala Badawi, Hanem Ahmed, Ahmed Ismail, Amira Helmy, Afkar Badawy, Manal Diab, Laila Abuel-Fadl and Aisha Abu-Aitta (2008). Diagnostic performance of different assays for detection of Chlamydia trachomatisin in patients with chronic cystitis and cancer bladder. Departments of  Microbiology, Biochemistry, Urology, Electron Microscopy and Pathology, Theodor Bilharz Research Institute.  Research Journal of Medicine and Medical Science; 3 (1): 1-13. http://www.insinet.net/jasr.html
102.  Hala Badawi, Hanem Ahmed, Ahmed Ismail, Manal Diab, Magd Moubarak,  Afkar Badawy, Mohamed Saber (2008).  Role of human papillomavirus types 16, 18, and 52 in recurrent cystitis and urinary bladder cancer among Egyptian patients. Departments of  Microbiology, Biochemistry, Urology and Pathology, Theodor Bilharz Research Institute.  Medscape J Med;  10 (10):232.  http://www.medscape.com 
103.  Maisa Omar,  Samah Saad El-Din, Nevine Fam, Manal Diab, Mohamed Shemis, Manar Raafat, Moataz Seyam, Moataz Hassan,  Afkar Badawy, Maha Akl, Mohamed Saber (2008): SEN virus infection in Egyptian chronic hepatitis C and haemodialysis patients. Departments of Microbiology, Biochemistry, Nephrology Gastroenterology and Hepatology and Pathology, Theodor Bilharz Research Institute.    Medscape J Med; 10 (12): 290. http://www.medscape.com www.PubMedCentral.gov
104.  Botros S., Hammam O., El-Lakkany N.M., Seif El-Din S.H., Ebeid F. (2008). Schistosoma haematobium (Egyptian strain): Rate of development and effect of praziquantel treatment. J. Parasitol. 94: 386-394.
105.  Hammam O., Aziz A., Roshdy M., Abdel Hadi A. (2008). Possible role of cyclooxygenase-2 in schistosomal and non-schistosomal-associated bladder cancer. Medscape. J. Med. 10 (3):60.
106.  Hadi A., Hammam O.A., Noh A. (2008). Histopathological changes and DNA pattern in esophageal and gastric mucosa before and after treatment of esophageal and gastric varices. Australian J. Basic Appl. Sci. (AJBAS). 2: 658-671.
107.  Hassan E., Hegazy A., Moussa M., Abdel-Wahab N., Seif S. (2008): Effect of garlic on tumor invasion and metastatic potential in induced colon carcinogenesis in rats: Histopathological and immunohistochemical study. JASMR. 3: 11-19.
108.  Diab M., El-Din S.S., Aboul-Fadl L., Moussa M., Omran Z., Shemis., El-Ghannam,  M. El-Ray A., Badawi A., El-Defrawi I., El-Sherbini E., Saber M. (2008). Inducible nitric oxide synthase expression in Helicobacter pylori CagA+ strains infections". E. J. Micro. 17: 605-613.
110.  Bassiouny A, Abo El-Hassan S, Moussa M, El-Ahwany E, Helal E, Taha A, Helmy AH, Kamel M and El-Bassiouni N (2009). Down-regulation of intrahepatic CD16+ and CD56+ immune cells in chronic hepatitis C virus infection and HCV-related hepatocellular carcinoma. Arch Med Sci, 5 (3): 321-328.
111.  Shaker OG, Hammam O, Saleh A, El Leithy T and Wishahi M (2009).  Possible role of telomerase and sFas in pathogenesis of various bladder lesions associated with schistosomiasis. Clinical Biochemistry Journal, 42 (9): 864-872.
112.  Moussa M, Omran Z, Nosseir M, Lotfy A and Swellam T (2009). Cyclooxygenase-2 expression  on urothelial and inflammatory cells of cystoscopic biopsies and urine cytology  as a possible predictive marker for bladder carcinoma. Acta Pathol Microbio. Immunol Scandinavica (APMIS), 117:  45-52.
113.  Bekheet IW, Madkour ME, Abdel Ghaffar N,  Nosseir MM,   Moussa MM, Ibraheim RA and Ateya ME (2009). The role of myeloperoxidase  in hepatitis C virus infection and associated liver cirrhosis. Open J Trop Med (Bentham) Bakistan,  2:  1-7.
114.  Elkhafif N, Voss N, Hammam OA, Akl M, Boehm S, Yehia H, Mansy S,  El Bendary O and El Fandy G (2009). Differentiation and homing of transplanted bone marrow cells in livers of murine schistosomiasis. Australian Journal of Basic and Applied Science (AJBAS), 2(4): 1362-1372.
115.  Akl  MM, Hammam OA, Mohamed HS, El Baz HG, Demerdash Z, Atta R and Shaker Z (2009). Localization of Schistosoma mansoni antigen confirms the frequent coexistence of hepatic schistosomiasis with chronic viral hepatitis C. An immuno-histochemical study. Accepted for publication in Australian Journal of Basic and Applied Science (AJBAS) at 4-1-2009.
116.  El Bassiouny A, Ahwany E, Abou Shousha T, Moussa M, El Bassiouni N, Maher K, Galli A, Youssef M, and Zada S (2009). Hepatic mRNA Expression of Histone (H3): An Early Predictor of Tumorgenic Changes in Chronic Hepatitis C.  Arch Med Sci,  5 (4): 1-7.
117.  Atta HM, Al-Hendy A, Salama SA, Shaker OG and Hammam OA (2009). Low-dose simultaneous delivery of adenovirus encoding HGF and VEGF in dogs enhances liver proliferation without systemic growth factor elevation. Liver International, 29 (7): 1022-1030.
118.  Botros SS, El-Lakkany NM, Badawy AA, Mahmoud SS, Ebeid FA and Fenwick A (2009). Mirazid shows insignificant activity against ovine fascioliasis. Ann Trop Med Parasitol, 103 (7): 605-616.
119.   Hammam O, El Ganzoury H, Abdel Hadi A and Akl M (2009). Immunohistochemical Study of Caspase 3 and Cyclin D1 in Bilharzial Bladder Cancer and Their Significance. Australian Journal of Basic and Applied Science (AJBAS), 3 (2): 1198-1205.
120.   Badawi H, Ahmed H, Aboul Fadl L, Moubarak M, Helmy A, El-Khafif N, Ismail A, Badawy A, Omar M and Saber M (2009). Performance of different cytomegalovirus diagnostic assays in bladder cancer patients with schistosomiasis. Medscape Archives of Medical Sciences Accepted on 19 May, 2009. www.archives of medical science.com
121.   Zakaria S, Youssef M, Moussa M, Akl M, El-Ahwany E, El-Raziky M, Mostafa O, Helmy AH and El-Hindawi A (2010). Value of alpha-smooth muscle actin and glial fibrillary acidic protein in predicting early hepatic fibrosis in chronic hepatitis C virus-infection. Arch Med Sci, 5 (4): 1-7.
122.  Badawi H, Ahmed H, Aboul Fadl L, Helmy A, Fam N, Diab M, Ismail A, Badawy A and Saber M (2010). Herpes simplex virus type-2 in Egyptian patients with bladder cancer or cystitis.  Acta Pathologica Microbiologica et Immunologica Scandanivica (APMIS), 118: 37-44. 
123.  El Ray A, Moucari R, El Ghannam M,  Taha AA,  Saber MA,  Akl M, Asselah T,  Atta R, Shemis M,  Radwan AS,  Ghali A and  Paradis V (2010). Insulin resistance: A major predictor of significant liver fibrosis in Egyptian patients with genotype 4 chronic hepatitis C. Journal of Hepatology, 52: 409-409.
124.   Ghanem L Y, Dahmem U, Dirch O, Nosseir MM, Mahmoud SS and Mansour WA (2010). Does granulocyte-colony stimulating factor administration induce damage or repair response in schistosomiasis?. World J Hepatol, 2 (12): 434-441.
125.   Elkhafif N, Voss B, Hammam O, Yehia H, Mansy S, Akl M, Boehm S, Mahmoud S, El Bendary O and El Fandy G (2010). Homing of transplanted bone marrow cells in livers of Schistosoma mansoni infected mice. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 118 (4): 277.
126.   Toima S, Saleh A, Madkour M, Hammam O and Abd El-Raouf E (2010): Role of hepcidin in anemia of patients with chronic hepatitis C. Journal of American Science, 6 (12):145-154.
127.   Botros SS, Hammam O, Mahmoud M and Bergquist R (2010). Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohisto-chemical assessment.  Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 118 (9): 692-702.
128.   El-Baz HG, Kamel MM, Hammam OA and El-Baz AG (2010): Potentials of Transforming Growth Factors-Alpha and Beta-1 in Predicting the Clinical Outcome of Bladder Carcinoma. International Journal of Immunological Studies (IJIS), 1(2): 169- 182.
129.   Hammam O, Abdel Aziz I, Mahmoud O, Zahran M, Alkholy A, Abdel Hadi A, Akl M, Wishahi M, Voss B and Boehm S (2010): Her 2/Neu gene and VEGF in bladder cancer in Egypt: Relationship to schistosomiasis.  Journal of American Science, 6 (12): 927-93.
130.   Bassiouny AE, Nosseir MM, Zoheiry MK, Ameen NA, Abdel Hadi AM, Ibrahim IM, Zada S, El Deen AH and El Bassiouni NE (2010): Differential expression of cell cycle regulators in HCV infection and related hepatocellular carcinoma. World J Hepatology, 27; 2 (1): 32-41.
131.   El Bassiouny AE, El-Ahwany EG, Zoheiry MK, Nosseir MM,  Ibrahim RA, Ibrahim IM, Zada SK and El-Bassiouni NE (2011). Circulating bone marrow derived fibrocytes contribute to the expression of myofibroblast pool in HCV-mediated liver fibrosis. Journal of Hepatology, 54: 131-132.
132.   Elkhafif N, El Baz H, Hammam O, Hassan S, Salah F, Mansour W, Mansy S, Yehia H, Zaki A, Magdy R (2011): CD133 (+) human umbilical cord blood stem cells enhance angiogenesis in experimental chronic hepatic fibrosis. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), 119 (1): 66-75.
133.   Shaker OG, Hammam OA, El Leithy TR, El Ganzoury H, Wishahi MM, Mikhailidis DP (2011). Molecular markers and bladder carcinoma: Schistosomal and non-schistosomal. Clinical Biochemistry, 44 (2-3): 237-44.
134.   Roshdy M, Hammam O, Wishahi M and Nour H (2011). Expression of transforming growth factor beta-1 protein and its receptor in tissue of patients with bladder cancer associated with scistosomiasis or not associated. Current Urology, 5: 33-40.
135.   Hammam O, El Badrawy N, El Ghanam M, Hassan M, Safwat W, Anas A (2011). Micro vascular density MVD-CD34 and VEGF expression in the liver of patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma. Journal of American Science; 7 (6): 808-815
136.   El-Lakkany NM, El-Maadawy WH, Ain-Shoka AA, Badawy AA, Hammam OA and Ebeid FA (2011). Potential antifibrotic effects of AT1 receptor antagonist, losartan, and/or praziquantel on acute and chronic experimental liver fibrosis induced by Schistosoma mansoni. Clinical and Experimental Pharmacology and Physiology, 38 (10): 695.
137.   Ma N, Thanan R,  Kobayashi H, Hammam O,  Wishahi M, El Leithy T, Hiraku Y,  Amro E,  Oikawa S, Ohnishi S, Murata M and  Kawanishi S (2011). Nitrative DNA damage and Oct3/4 expression in urinary bladder cancer with Schistosoma haematobium infection. Biochemical and Biophysical Research Communicat, 414 (2): 344.
138.   El-Lakkany,  Seif  El-Din SH,  Sabra AN, and  Hammam  OA (2011). Pharmacodynamics of mefloquine and praziquantel combination therapy in mice harbouring juvenile and adult Schistosoma mansoni. Memorias do Instituto Oswaldo Cruz, 106(7): 814.
139.  Hammam O, Zahran M, Mahmoud O, Aly S, Hosny K, Helmy A and Anas A (2012). The Role of fas/fas ligand system in the pathogenesis of liver cirrhosis and hepatocellular carcinoma. Hepatitis Monthly; 12 (11): 6132.
140.   Elmansy H, Kotb A, Hammam O, Abdelraouf H, Salem H, Onsi M and Elleithy T (2012).  Prognostic impact of apoptosis marker Fas (CD95) and its ligand (FasL) on bladder cancer in Egypt: Study of the effect of schistosomiasis. E Cancer Medical Science; 6: 278.  
141. El-Ansary M, Abdel-Aziz I, Mogawer S, Abdel-Hamid S, Hammam O, Teaema S and Wahdan M (2012). Phase II trial: Undifferentiated versus differentiated autologous mesenchymal stem cells transplantation in Egyptian patients with HCV induced liver cirrhosis.  Stem Cell Rev and Rep, 8 (3): 972-981.
142. El-Lakkany NM, Hammam OA, El-Maadawy WH, Badawy AA, Ain-Shoka AA and Ebeid FA (2012). Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis. Parasit Vectors; 11; 5: 9.
143. Thanan R, Murata M, Ma N, Hammam O, Wishahi M, El Leithy T, Hiraku Y, Oikawa S and Kawanishi S (2012). Nuclear localization of COX-2 in relation to the expression of stemness markers in urinary bladder cancer. Mediators Inflammation, 165879. [PubMed]. (doi: 10.1155/2012/165879. Epub Accepted Apr 10).
144. Shaker OG, Hammam OA and Wishahi MM (2012). Is there a correlation between HPV and urinary bladder carcinoma?. Biomedicine and Pharmacotherapy. Accepted for Publication on Dec 7. {PubMed}.
145. Hedya MS, Nasr MM, Ezzat H, Hamdy HM, Hassan AM and Hammam O (2012). Histopathological findings in appendectomy specimens: A retrospective clinicopathological analysis. J Egypt Soc Parasitol, 42 (1): 157-64.
146. El Ghanam M, El Badrawy N, Hammam O, Hassan M and Anas A (2012). Tissue expression of PCNA and Caspase3 in the liver in patients with chronic hepatitis, cirrhosis and hepatocellular carcinoma. Life Science Journal, 9 (2): 1083-1087. 
147.Mahmoud M, Hammam O and El-Sherbiny M (2012). Immunohistological and pharmacological studies of anti-inflammatory drugs in experimental schistosomiasis. Accepted for Publication in African Journal of Pharmacy and Pharmacology (AJPP). October 14, 2012 (Google).
148. El-Raay A, Marcelain P, Akl M, Paradie V, Atta R and El-Ghannam M (2012).  Insulin Resistance: A major factor associated with significant liver fibrosis in Egyptian patients with Genotype 4 chronic hepatitis C. Accepted in European Journal of Gastroenterology and Hepatology on December 2012.
152.           Abdel Haleem H, Zayed N, Abdel Hafez H, Fouad A, Akl M,  Hassan M, Hammam O, Morsy A, Saleh A, Seyam M, Zakaria Z and Zakaria S (2013). Evaluation of the diagnostic value of serum and tissue apoptotic cytokeratin-18 in patients with chronic hepatitis C.  Arab Journal of Gastroenterology, 14 (2): 68.  
153.   Shaker O, Hammam O, Wishahi M and Roshdi M (2013). TGF-B1 pathway as biological marker of bladder carcinoma schistosomal and non-schistosomal. Urologic Oncology: Seminars and Original Invest, 31(3): 372.


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