The Pathology Department in Theodor Bilharz Research Institute is one of the basic pillars of the clinical and research activities.It has a highly qualified and well trained staff, having long years of experience. The department is well equipped by the most recent tools used in the field of pathology world-wide. We used to hold periodic training programs, and we always welcome and encourage conjoint work with our colleagues in universities and research centers.



SERVICES

Department Structure and Facilities:
1.     Histo and cytopathology diagnosis unit.
2.     Frozen pathology diagnosis unit.
3.     Immunohistochemistry application unit.
4.     DNA and molecular pathology unit.
5.     Cytogenetic unit.

Running Techniques:
·        Routine pathological examination and diagnosis of any surgically excised tissue specimen, swelling or organ.
·        Cytological diagnosis of all fluid samples using cytospin smears technique.
·        Fine needle aspirate cytopathological diagnosis for any swelling and for liver lesions as focal hepatic defects, hydatid cysts, amoebic and chronic abscesses..etc. This technique is also performed by the pathologists for patients with any apparrant subcutaneous body swelling.
·        Frozen section immediate diagnosis of surgically resected specimens for patients under anaesthesia.
·        Immunohistochemical technique used for detection of different tumor markers.
·        Detection of DNA content of the nuclei of different cells  using Cell Image Analysis system by staining the slides with fulgen stain ( using hard ware ).
·          Morphometrical assessement of the cell parameters as nuclei area, cytoplasmic area, blood vessels, peimeter of different pathological lesions, for detection of early neoplasia, staging and prognosis using Cell Image Analysis System (software KS 400).
·        Semiquatitative estimation of fibrosis in different pathological lesions using Cell Image Analysis System (software KS 400).
·        Pathological evaluation of the effect of different kinds of therapeutic regimens in different diseases on body organs.
·        Using In Situ Hybridization Technique for detection of mRNA of cell proteins, viruses, tumor markers in different pathological lesions.
·        Using FISH (flourescent in situ hybridization) technique for tracing the transplanted stem cells, detection of gene and chromosomal mutation and abnormalities in different premalignant and malignant lesions.
Training Facilities:
·        On routine processing and preparation of biopsy specimens for pathological diagnosis (fixation, processing, embedding into paraffin blocks, cutting on microtome and staining).
·        On frozen section preparation.
·        On cytopathology.
·        On immunohistochemical and molecular pathology techniques (as ISH and FISH) in the field of pathology.
·        On image analysis techniques (quantitation of nuclear DNA and morphometrical measurements) and its application in the field of pathology.
Scope of Services:
·        Routine histopathological and cytopathological diagnosis
·        Immunohistochemical technique for certain pathological lesion for more pathological details.
·        DNA and morphometrical assessement of different pathological lesions for detection of early neoplasia, staging and prognosis.
·        Semiquatitative estimation of fibrosis in different pathological lesions.
·        Pathological evaluation of the effect of different kinds of therapeutic regimens in different diseases on body organs.

Routine out and in-patient services:

Routine pathological examination and diagnosis of any surgically excised tissue specimen, swelling or organ.
·        Cytological diagnosis of all fluid samples using cytospin smears technique.
·        Fine needle aspirate cytopathological diagnosis for any swelling and for liver lesions as focal hepatic defects, hydatid cysts, amoebic and chronic abscesses..etc. This technique is also performed by the pathologists for patients with any apparrant subcutaneous body swelling.
·        Frozen section immediate diagnosis of surgically resected specimens for patients under anaesthesia.

·        Immunohistochemical technique for certain pathological lesion for more pathological details.

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